Title of article
The reaction of thioesters with nitriles. A new synthetic approach to the preparation of substituted 4-alkylthio- and 4-arylthiopyrimidine derivatives
Author/Authors
Antonio Herrera، نويسنده , , Roberto Mart??nez-Alvarez، نويسنده , , Pedro Ramiro، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
6
From page
7331
To page
7336
Abstract
S-Alkyl and S-aryl thioesters react with nitriles in the presence of triflic anhydride to form substituted 4-alkylthio- and 4-arylthiopyrimidines. However, when methyl thiocyanate is used as nitrile, dithioimidocarbonates are formed. A mechanism to explain these differences is postulated.
Keywords
triflic anhydride , thioesters , alkylthiopyrimidines , arylthiopyrimidines
Journal title
Tetrahedron
Serial Year
2003
Journal title
Tetrahedron
Record number
1084279
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