Title of article :
A facile synthesis of 3-(substituted benzyl)piperidines
Author/Authors :
Béla ?gai، نويسنده , , Adrienn N?dor، نويسنده , , ?gnes Proszeny?k، نويسنده , , G?bor T?rk?nyi، نويسنده , , Ferenc Faigl، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2003
Abstract :
A convenient new method has been developed for preparation a series of 3-(substituted benzyl)piperidines by addition of substituted phenylmagnesium bromide to pyridine-3-carboxaldehyde followed by one pot deoxygenation and heteroaromatic ring saturation in the presence of palladium catalyst.
Keywords :
Grignard-reaction , Catalytic reduction , catalytic deoxygenation , 3-benzylpiperidine
Journal title :
Tetrahedron
Journal title :
Tetrahedron