Title of article
Practical enantioselective reduction of ketones using oxazaborolidine catalyst generated in situ from chiral lactam alcohol and borane
Author/Authors
Yasuhiro Kawanami، نويسنده , , Shinichi Murao، نويسنده , , Takahiko Ohga، نويسنده , , Nobuyo Kobayashi، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
4
From page
8411
To page
8414
Abstract
Reduction intermediate prepared in situ from chiral lactam alcohol and borane at room temperature was found to catalyze the borane reduction of various prochiral ketones with high enantioselectivity up to 98% ee.
Keywords
Enantioselective , Reduction , Asymmetric synthesis , lactam alcohol , Borane
Journal title
Tetrahedron
Serial Year
2003
Journal title
Tetrahedron
Record number
1084396
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