Title of article
Free radical-mediated vinyl amination: a mild, general pyrrolidinyl enamine synthesis
Author/Authors
Benjamin M. Nugent، نويسنده , , Amie L. Williams، نويسنده , , E.N. Prabhakaran، نويسنده , , Jeffrey N. Johnston، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
12
From page
8877
To page
8888
Abstract
The complete scope of free radical-mediated vinyl amination is described, using 5-exo-trig cyclizations of vinyl radicals to the nitrogen of azomethines. The focus is primarily on N,N-dialkyl enamines since their nucleophilicity renders them the most challenging enamines to synthesize using redox conditions. These studies establish several encouraging precedents for the broader application of this strategy.
Keywords
vinyl amination , Free radicals , Enamines , alkyne aminostannation , ?-stannyl enamine
Journal title
Tetrahedron
Serial Year
2003
Journal title
Tetrahedron
Record number
1084439
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