Title of article :
Regioselective reduction of N-alkyl-3-sulfonyl glutarimides to δ-lactams. Formal synthesis of (±)-paroxetine and (±)-tacamonine
Author/Authors :
Chung-Yi Chen، نويسنده , , Bo-Rui Chang، نويسنده , , Min-Ruei Tsai، نويسنده , , Meng-Yang Chang، نويسنده , , Nein-Chen Chang، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2003
Abstract :
A convenient method for the preparation of 4- or 5-substituted 3-sulfonyl-δ-lactams via regioselective reduction of N-alkyl-3-sulfonyl glutarimides is described. Formal synthesis of (±)-paroxetine and (±)-tacamonine is also reported.
Keywords :
tacamonine , glutarimide , regioselective reduction , ?-lactam , Paroxetine
Journal title :
Tetrahedron
Journal title :
Tetrahedron
