Title of article
Oxazolinyloxiranyllithium-mediated synthesis of highly strained heterocyclic compounds
Author/Authors
Renzo Luisi، نويسنده , , Vito Capriati، نويسنده , , Leonardo Degennaro، نويسنده , , Saverio Florio، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
6
From page
9713
To page
9718
Abstract
The addition reaction of α-lithiated oxazolinyloxiranes to nitrones has been investigated. 1,5,9-Trioxa-8,10-diazadispiro[2.0.4.3]undecanes formed in a completely diastereoselective manner upon treatment of α-lithiated oxiranes with nitrones. The lithiation of optically active trans and cis-oxazolinyloxiranes followed by the addition of a nitrone resulted in the formation of the same dispirocyclic compound. An explanation for the observed stereoselectivity is provided.
Keywords
Oxazolines , lithiation , oxiranes , Nitrones , Spiro compounds
Journal title
Tetrahedron
Serial Year
2003
Journal title
Tetrahedron
Record number
1084520
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