Author/Authors :
Kouji Kuramochi، نويسنده , , Seigo Nagata، نويسنده , , Hideyoshi Itaya، نويسنده , , Yasuaki Matsubara، نويسنده , , Takashi Sunoki، نويسنده , , Hiromi Uchiro، نويسنده , , Ken-ichi Takao، نويسنده , , Susumu Kobayashi، نويسنده ,
Abstract :
The generation and reaction of a lactone-derived oxiranyl anion is described. The aldol-type reaction of the epoxylactone and aldehydes was accomplished by a two-step procedure via the trimethylsilyl epoxylactone. The application of this methodology to the total synthesis of (+)-epolactaene and its analogs is described.
Keywords :
epolactaene , epoxylactone , TBAF , Aldol reaction
