Title of article
Rakanmakilactones A–F, new cytotoxic sulfur-containing norditerpene dilactones from leaves of Podocarpus macrophyllus var. Maki
Author/Authors
Hyun-Sun Park، نويسنده , , Naoki Yoda، نويسنده , , Haruhiko Fukaya، نويسنده , , Yutaka Aoyagi، نويسنده , , Koichi Takeya، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
7
From page
171
To page
177
Abstract
Six new S-containing norditerpene dilactones, rakanmakilactones A–F (), were isolated from the leaves of Podocarpus macrophyllus D. Don var. maki Endl., along with four known norditerpene dilactones (). Their structures, stereochemistry and absolute configurations were determined by spectroscopic studies (HRMS, IR, 1H, 13C and 2D NMR), and single-crystal X-ray analyses. Rakanmakilactones were found to have a cytotoxic effect against P388 murine leukemia cells.
Keywords
Rakanmakilactones A–F , norditerpene dilactone , Single-crystal X-ray analysis , Cytotoxicity , Podocarpus macrophyllus , Podocarpaceae
Journal title
Tetrahedron
Serial Year
2004
Journal title
Tetrahedron
Record number
1084625
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