Title of article
Hydrolytic and transglycosylation reactions of N-acyl modified substrates catalysed by β-N-acetylhexosaminidases
Author/Authors
Pavla Fialov?، نويسنده , , Lenka Weignerov?، نويسنده , , Jana Rauvolfova، نويسنده , , V?ra P?ikrylov?، نويسنده , , Andrea Pi?vejcov?، نويسنده , , Rüdiger Ettrich، نويسنده , , Marek Kuzma، نويسنده , , Petr Sedmera، نويسنده , , Vladim??r K?en، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
9
From page
693
To page
701
Abstract
The hydrolytic and transglycosylation capabilities of 35 fungal β-N-acetylhexosaminidases with p-nitrophenyl 2-amino-2-deoxy-β-d-glucopyranoside and its four N-acyl derivatives (CHO, COCH2OH, COCH2CH3, COCF3) as substrates were tested. The preparation of four novel p-nitrophenyl disaccharides from these unnatural substrates catalysed by enzymes from Aspergillus oryzae, Penicillium oxalicum and Talaromyces flavus represents a considerable extension of the synthetic potential of glycosidases.
Keywords
?-N-Acetylhexosaminidase , p-Nitrophenyl 2-acylamido-2-deoxy-?-d-glucopyranoside , Transglycosylation , N-Acyl modified substrate
Journal title
Tetrahedron
Serial Year
2004
Journal title
Tetrahedron
Record number
1084722
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