Title of article
Improved synthesis of 6-amino-6-deoxy-d-galactono-1,6-lactam and d-mannono-1,6-lactam from corresponding unprotected d-hexono-1,4-lactones
Author/Authors
Ludovic Chaveriat، نويسنده , , Imane Stasik، نويسنده , , Gilles Demailly، نويسنده , , Daniel Beaupère، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
3
From page
2079
To page
2081
Abstract
Regioselective bromination of unprotected d-galactono-1,4-lactone and d-mannono-1,4-lactone with PPh3/CBr4 led to 6-bromo-6-deoxy derivatives. These intermediates were treated with LiN3 and hydrogenated to give 6-amino-6-deoxy-d-galactono-1,6-lactam () and 6-amino-6-deoxy-d-mannono-1,6-lactam () in 74 and 67% overall yield, respectively.
Keywords
d-Galactono-1 , 4-lactone , 6-Bromo-6-deoxy-d-hexono-1 , 4-lactone , Seven-member azasugars , 4-lactones , 6-Amino-6-deoxy-d-galactono , d-mannono-1 , 6-lactams , d-mannono-1
Journal title
Tetrahedron
Serial Year
2004
Journal title
Tetrahedron
Record number
1084985
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