Title of article
Synthesis of enantiomeric-pure cyclohexenyl nucleoside building blocks for oligonucleotide synthesis
Author/Authors
Ping Gu، نويسنده , , Carsten Griebel، نويسنده , , Arthur Van Aerschot، نويسنده , , Jef Rozenski، نويسنده , , Roger Busson، نويسنده , , Hans-Joachim Gais، نويسنده , , Piet Herdewijn، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
13
From page
2111
To page
2123
Abstract
Lipases were used for the resolution of (±) (4aR, 7R, 8aS)-2-phenyl-4a,7,8,8a-tetrahydro-4H-1,3-benzodioxine. This separation was carried out on preparative scale and used for the synthesis of eight phosphoramidites of cyclohexenyl nucleosides (d- and l-series).
Keywords
Cyclohexenyl nucleosides , Enzymatic resolution , Mitsunobu reaction , Phosphoramidite
Journal title
Tetrahedron
Serial Year
2004
Journal title
Tetrahedron
Record number
1084990
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