Title of article
A convenient ring formation of 3-aryl-2,2-dialkyl-2,3-dihydrobenzofurans from phenols and 2-aryl-2,2-dialkylacetaldehydes
Author/Authors
Makoto Yamashita، نويسنده , , Yujirou Ono، نويسنده , , Hiroyuki Tawada، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
7
From page
2843
To page
2849
Abstract
A new and simple route for the preparation of 3-aryl-2,2-dialkyl-2,3-dihydrobenzofurans from phenols is described. In the presence of an acid catalyst phenols react with 2-aryl-2,2-dialkylacetaldehydes, prepared in good yield from 2-arylacetonitriles in 2 steps, to give 3-aryl-2,2-dialkyl-2,3-dihydrobenzofurans. Electron-donating substituents were required on the phenols in order to give 3-aryl-2,2-dialkyl-2,3-dihydrobenzofurans in good yield.
Keywords
Phenols , 2 , Wagner–Meerwein rearrangement , Aldehydes , 3-Dihydrobenzofurans
Journal title
Tetrahedron
Serial Year
2004
Journal title
Tetrahedron
Record number
1085161
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