CeCl3·H2O/NaI-Promoted stereoselective synthesis of 2,4-disubstituted chiral tetrahydroquinolines

d-Glycals readily undergo cyclization with aryl amines in the presence of CeCl3·7H2O–NaI under mild and neutral conditions to afford a novel sugar derived tetrahydroquinoline derivatives in good yields with high stereoselectivity. The stereochemistry of the products was assigned by using various NMR studies.