Chemistry of renieramycins. Part 6: Transformation of renieramycin M into jorumycin and renieramycin J including oxidative degradation products, mimosamycin, renierone, and renierol acetate

The transformation of renieramycin M () into renieramycin J () and jorumycin () is presented along with the results of antiproliferative assay data. The chemical stability and the oxidative degradation of and renieramycin E () to generate simple isoquinoline alkaloids, such as mimosamycin (), renierol acetate (), and renierone () are also described.