Title of article
N–H Insertion reactions of rhodium carbenoids. Part 5: A convenient route to 1,3-azoles
Author/Authors
James E. Davies، نويسنده , , Peter D. Kane، نويسنده , , Christopher J. Moody، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
11
From page
3967
To page
3977
Abstract
Dirhodium(II) carboxylate catalysed reaction of diazocarbonyl compounds in the presence of primary amides results in the formation of α-acylaminoketones (12 examples) by N–H insertion reaction of the intermediate rhodium carbene. The 1,4-dicarbonyl compounds are readily converted into structurally diverse oxazoles (11 examples) by cyclodehydration, thiazoles (10 examples) by treatment with Lawessonʹs reagent, or imidazoles (2 examples) by reaction with ammonia or methylamine.
Keywords
oxazole , Imidazole , Thiazole , Heterocyclic
Journal title
Tetrahedron
Serial Year
2004
Journal title
Tetrahedron
Record number
1085418
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