Title of article
An efficient route to 6-(het)aryl-2-methyl-2,3-dihydro-1H-pyridin-4-ones as potential nAChRs ligands
Author/Authors
Nicolas Leflemme، نويسنده , , Patrick Dallemagne، نويسنده , , Sylvain Rault، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
5
From page
4861
To page
4865
Abstract
A new efficient pathway to synthesise 6-(het)aryl-2-methyl-2,3-dihydro-1H-pyridin-4-ones is described. This reaction sequence involved, as a key step, a Suzuki cross-coupling reaction between various boronic acids and an 6-iodo-2,3-dihydropyridin-4-one. A final deprotecting step furnished the attempted products.
Keywords
Heterocycles , Dihydropyridinone , Suzuki reaction , Cross-coupling , Boronic acids
Journal title
Tetrahedron
Serial Year
2004
Journal title
Tetrahedron
Record number
1085601
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