Title of article
A new approach to isoindoloisoquinolinones. A simple synthesis of nuevamine
Author/Authors
Anne Moreau، نويسنده , , Axel Couture، نويسنده , , Eric Deniau، نويسنده , , Pierre Grandclaudon، نويسنده , , Stéphane Lebrun، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
8
From page
6169
To page
6176
Abstract
A convenient and versatile short step synthesis of isoindoloisoquinolinones, illustrated by the total synthesis of the alkaloid nuevamine , is described. The tetracyclic lactam compounds were obtained by a tactical combination of the Parham procedure for the elaboration of the isoindolinone template and an aryne-mediated cyclization giving rise to the nitrogen containing six-membered heteroring unit.
Keywords
Parham procedure , arynes , isoindolinones , Alkaloids
Journal title
Tetrahedron
Serial Year
2004
Journal title
Tetrahedron
Record number
1085820
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