Title of article
Enzyme catalyzed hydroxymethylation of aromatic aldehydes with formaldehyde. Synthesis of hydroxyacetophenones and (S)-benzoins
Author/Authors
Ayhan S Demir، نويسنده , , Peruze Ayhan، نويسنده , , A Cigdem Igdir، نويسنده , , A.Nese Duygu، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
4
From page
6509
To page
6512
Abstract
Benzaldehyde lyase from the Pseudomonas Fluorescens catalyzed reaction of aromatic aldehydes with formaldehyde providing 2-hydroxy-1-arylethan-1-one in high yields via an acyloin linkage. Kinetic resolution of rac-benzoins with formaldehyde providing (S)-benzoins and 2-hydroxy-1-arylethan-1-one via C–C bond cleavage and a bond formation reaction.
Keywords
Carboligation , Benzoin , Enzyme catalysis , Hydroxy ketones , hydroxymethylation
Journal title
Tetrahedron
Serial Year
2004
Journal title
Tetrahedron
Record number
1085849
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