Title of article
Nakiterpiosin and nakiterpiosinone, novel cytotoxic C-nor-D-homosteroids from the Okinawan sponge Terpios hoshinota
Author/Authors
Toshiaki Teruya، نويسنده , , Satoru Nakagawa، نويسنده , , Tomoyuki Koyama، نويسنده , , Hirokazu Arimoto، نويسنده , , Masaki Kita، نويسنده , , Daisuke Uemura، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
5
From page
6989
To page
6993
Abstract
Two new cytotoxic compounds, nakiterpiosin () and nakiterpiosinone (), were isolated from the Okinawan sponge Terpios hoshinota. Their structures were determined by spectroscopic analysis. The absolute stereostructure of was also determined by a modified Mosherʹs method. Nakiterpiosin () and nakiterpiosinone () showed potent cytotoxicity against mouse lymphocytic leukemia cell (P388).
Keywords
C-nor-D-homosteroid , Nakiterpiosin , The sponge Terpios hoshinota , Nakiterpiosinone , Cytotoxicity
Journal title
Tetrahedron
Serial Year
2004
Journal title
Tetrahedron
Record number
1085894
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