Synthesis of complex alkoxyamines using a polymer-supported N-hydroxyphthalimide

The synthesis of a polymer-supported N-hydroxyphthalimide is described. The polystyrene-bound N-hydroxyphthalimide resin has been used to prepare complex alkoxyamines exhibiting both stereochemical and positional diversity. Methods for efficient condensation of complex alkoxyamines with aldehydes and ketones are also outlined.