Title of article
Synthesis of a PNA-encoded cysteine protease inhibitor library
Author/Authors
François Debaene، نويسنده , , Lorenzo Mejias، نويسنده , , Jennifer L. Harris، نويسنده , , Nicolas Winssinger، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
14
From page
8677
To page
8690
Abstract
Peptide nucleic acids (PNAs) have been used to encode a combinatorial library whereby each compound is labeled with a PNA tag which reflects its synthetic history and localizes the compound upon hybridization to an oligonucleotide array. We report herein the full synthetic details for a 4000 member PNA-encoded library targeted towards cysteine protease.
Keywords
Microarrays , Combinatorial chemistry , Protease inhibitors , Peptide nucleic acid
Journal title
Tetrahedron
Serial Year
2004
Journal title
Tetrahedron
Record number
1087081
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