Title of article
A facile synthesis of 4-, 5- and 6-chloromethyl-1H-indole-2-carboxylates: replacement of a sulfonic acid functionality by chlorine
Author/Authors
Béla Pete، نويسنده , , Gyula Parlagh، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
9
From page
8829
To page
8837
Abstract
Valuable new synthetic intermediates, 4-, 5- or 6-chloromethyl-1H-indole-2-carboxylates, were prepared by the facile elimination of SO2 from 2-ethoxycarbonyl-1H-indole-4-, 5- or 6-methanesulfonic acids, respectively, easily accessible by Fischer-type indolization.
Keywords
4-(Chloromethyl)indoles , Japp-Klingemann reaction , 5-(Chloromethyl)indoles , 6-(Chloromethyl)indoles , Fischer synthesis , Desulfination
Journal title
Tetrahedron
Serial Year
2004
Journal title
Tetrahedron
Record number
1087094
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