Title of article
Efficient solution phase parallel synthesis of norstatine analogs
Author/Authors
Michael V. Voronkov، نويسنده , , Alexander V. Gontcharov، نويسنده , , Zhi-Min Wang، نويسنده , , Paul F. Richardson، نويسنده , , Hartmuth C. Kolb، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
6
From page
9043
To page
9048
Abstract
The reaction of glycidic amides with various functionalized nitriles to afford norstatine analogs in a regio- and diastereoselective fashion (43–99% yield) is described. Utilizing this chemistry, a 20 membered solution phase library was prepared in two steps featuring three points of diversity.
Keywords
Epoxide , Norstatine , nitrile , solution phase combinatorial chemistry
Journal title
Tetrahedron
Serial Year
2004
Journal title
Tetrahedron
Record number
1087115
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