Title of article
Copper carbenoid mediated N-alkylation of imidazoles and its use in a novel synthesis of bifonazole
Author/Authors
Erick Cuevas-Ya?ez، نويسنده , , Juan-Manuel Serrano، نويسنده , , Gloria Huerta-Angeles، نويسنده , , Joseph M. Muchowski، نويسنده , , Raymundo Cruz-Almanza، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
6
From page
9391
To page
9396
Abstract
1H-Imidazoles are readily N-alkylated by a Cu(acac)2 mediated reaction with α-diazocarbonyl compounds or with diazoalkanes generated in situ from the corresponding p-toluensulfonyl hydrazones. The antifungal agent bifonazole was prepared by the latter method.
Keywords
copper , carbenoid , Imidazole , Bifonazole
Journal title
Tetrahedron
Serial Year
2004
Journal title
Tetrahedron
Record number
1087147
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