Title of article
Synthesis and applications of chiral bis-THF in asymmetric synthesis
Author/Authors
Alexandre Alexakis، نويسنده , , Axel Tomassini، نويسنده , , Stéphane Leconte، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
6
From page
9479
To page
9484
Abstract
The synthesis of enantiopure bis-THF is described, starting from d-mannitol. Bis-THF is used as chiral ligand for organolithium reagents in four different reactions. The enantioselectivity provided by this ligand is moderate, and the asymmetric induction is in line with the expected model.
Keywords
Asymmetric synthesis , Chirality , Diether , Organolithium reagents , Coordination
Journal title
Tetrahedron
Serial Year
2004
Journal title
Tetrahedron
Record number
1087158
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