Author/Authors :
Biing-Jiun Uang، نويسنده , , Hsin-Pin Fu، نويسنده , , Chyuan-Der Hwang، نويسنده , , Chun-Wei Chang، نويسنده , , Chun-Tzu Yang، نويسنده , , Der-Ren Hwang، نويسنده ,
Abstract :
A highly enantioselective addition of trimethylsilylcyanide to aldehydes catalyzed by chiral titanium complexes is described. The chiral titanium complexes were prepared in situ from Ti(OiPr)4 and β-hydroxyamide ligands, that could easily be synthesized from ketopinic acid and C2 symmetrical chiral diamines in a small number of steps.
Keywords :
Titanium complex , ?-Hydroxyamide , Asymmetric catalysis , cyanohydrin
