Title of article
Synthesis of N-aryl-aza-crown ethers via Pd-catalyzed amination reactions of aryl chlorides with aza-crown ethers
Author/Authors
Sameer Urgaonkar، نويسنده , , John G. Verkade، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
6
From page
11837
To page
11842
Abstract
The Pd2(dba)3/P(i-BuNCH2CH2)3N () catalyst system effectively catalyzes the coupling of aza-crown ethers with electronically diverse aryl chlorides, affording N-aryl-aza-crown ethers in good yields. The Pd2(dba)3/P(i-BuNCH2)3CMe () catalyst system containing the more constrained bicyclic triaminophosphine is useful for aryl chlorides possessing base-sensitive ester, nitro, and nitrile functional groups.
Keywords
Proazaphosphatrane , N-Aryl-aza-crown ether , Buchwald–Hartwig amination , Bicyclic triaminophosphine , Palladium
Journal title
Tetrahedron
Serial Year
2004
Journal title
Tetrahedron
Record number
1087402
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