Title of article
A modified Robinson annulation process to α,α-disubstituted-β,γ-unsaturated cyclohexanone system. Application to the total synthesis of nanaimoal
Author/Authors
Hsing-Jang Liu، نويسنده , , Tai Wei Ly، نويسنده , , Chia-Liang Tai، نويسنده , , Jen-Dar Wu، نويسنده , , Jinn-Kwei Liang، نويسنده , , Jiunn-Cheh Guo، نويسنده , , Nai-Wen Tseng، نويسنده , , Kak-Shan Shia، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
18
From page
1209
To page
1226
Abstract
4-Cyano-2-cyclohexenones were found to be susceptible to reductive alkylation reactions, giving the corresponding 2,2-disubstituted-3-cyclohexenone derivatives in a completely regioselective manner. This newly developed methodology has been successfully applied towards the total synthesis, in racemic form, of the marine natural product nanaimoal.
Keywords
Alkylation , Reduction , cyano compounds , Ketones
Journal title
Tetrahedron
Serial Year
2003
Journal title
Tetrahedron
Record number
1087531
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