Title of article
Synthesis of perfragilin A, B and some analogues
Author/Authors
Vitor F Ferreira، نويسنده , , Aeri Park، نويسنده , , Francis J. Schmitz، نويسنده , , Fred A Valeriote، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2003
Pages
9
From page
1349
To page
1357
Abstract
Synthesis of the cytotoxic isoquinoline quinone perfragilin A, an improved synthesis of perfragilin B and preparation of some analogues of both these compounds are described. Cytotoxicity evaluation of a number of the products is reported. The regioselectivity in Diels–Alder reactions of differently substituted benzoquinones with 2-aza-1,3-bis(t-butyldimethylsilyloxy)-1,3-butadiene is described.
Keywords
Synthesis , Antitumor , Cytotoxicity , Diels–Alder , quinines , isoquinoline , Regioselectivity
Journal title
Tetrahedron
Serial Year
2003
Journal title
Tetrahedron
Record number
1087547
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