Title of article :
Diastereoselective synthesis of 2-oxiranyl and 2-aziridinyl thiazoles
Author/Authors :
Fabio Bona، نويسنده , , Luisella De Vitis، نويسنده , , Saverio Florio، نويسنده , , Ludovico Ronzini، نويسنده , , Luigino Troisi، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2003
Abstract :
2-Chloroalkylthiazolyllithiums, prepared by deprotonating the 2-chloroalkylthiazoles with n-BuLi at −78°C in THF, add to ketones or imines affording in ‘one-pot’ oxiranes and aziridines in a Z stereoselective manner.
Keywords :
thiazolylalkyloxiranes , thiazolylalkylaziridines , Carbanion , Nucleophilic addition
Journal title :
Tetrahedron
Journal title :
Tetrahedron
