Title of article :
Chemistry of indoles carrying a basic function. Part 8: A new approach to the ergoline skeleton
Author/Authors :
M?ria Incze، نويسنده , , Istv?n Moldvai، نويسنده , , Eszter Temesv?ri-Major، نويسنده , , G?bor D?rnyei، نويسنده , , M?ria Kajt?r-Peredy، نويسنده , , Csaba Sz?ntay، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2003
Abstract :
Starting from N-pivaloyl-Uhleʹs ketone a new synthetic approach to the ergoline skeleton has been elaborated. Ring D of the tetracyclic skeleton was formed by an intramolecular Dieckmann-condensation of a diester, obtained in a Reformatsky reaction of a properly substituted derivative of N-pivaloyl Uhleʹs ketone followed by elimination of water.
Keywords :
Alkaloids , ergolines , modified Reformatsky reaction , Cyclisation , Dieckmann condensation
Journal title :
Tetrahedron
Journal title :
Tetrahedron
