Chiral ferrocene cyanohydrin derivatives—access to novel intermolecularly linked and intramolecularly bridged ferrocene derivatives

By reduction of the cyano group in (R)-(cyanohydroxymethyl)ferrocene and (R,R)-1,1′-bis(cyanohydroxymethyl)ferrocene, amines were obtained giving access to several new diamine and diamide bridged chiral ferrocene derivatives. As a representative for an intramolecularly bridged ferrocene compound bearing two chiral centres was obtained with excellent optical purity.