Author/Authors :
Zeng، Weikun نويسنده Medical Faculty, Kunming University of Science and Technology, Kunming, China , , Zhao، Xianchen نويسنده Medical Faculty, Kunming University of Science and Technology, Kunming, China , , Yu، Wenhai نويسنده Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, China , , He، Zhanlong نويسنده Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming, China , , Jing، Shenrong نويسنده Medical Faculty, Kunming University of Science and Technology, Kunming, China , , Huang، Fen نويسنده Medical Faculty, Kunming University of Science and Technology, Kunming, China ,
Abstract :
Background: Enteroviruses are among the most common viruses, which cause more than one billion infections worldwide. Enterovirus 92 (EV92) is a newly identified virus, about which few epidemiological data are available.
Objectives: The aim of this study was to investigate the echoviruses in captive rhesus macaques (Macaca mulatta) with acute diarrheal disease in the southwest of China.
Materials and Methods: Stool samples (246) of diarrheal monkeys were collected for detection of EV92 by reverse transcription PCR (RT-PCR) as well as analysis of the epidemiological characterizations.
Results: Sequence analysis indicated that echovirus shared the highest nucleotide identity (85%) with the EV92 strain isolated from the rhesus macaques with gastroenteritis from a US primate center. Phylogenetic analysis showed that the EV92 isolated in this study had clustered together with other echoviruses isolated from the primates.
Conclusions: The results suggested that EV92 as a new echovirus may cause acute diarrhea in M. mulatta.
