Title of article
Niobium(V) chloride-catalyzed C–H insertion reactions of α-diazoesters: synthesis of β-keto esters
Author/Authors
J.S. Yadav، نويسنده , , B.V. Subba Reddy، نويسنده , , B. Eeshwaraiah، نويسنده , , P.N. Reddy، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
4
From page
875
To page
878
Abstract
Aldehydes react readily with ethyl diazoacetate in the presence of 5 mol% of NbCl5 in dichloromethane to produce the corresponding β-keto esters in good yields with high selectivity. This method is very useful for the preparation of β-keto esters from both electron-rich as well as electron-deficient aromatic aldehydes under mild reaction conditions.
Keywords
Diazo ester , carbene insertion , Transition metal catalysis , ?-keto esters
Journal title
Tetrahedron
Serial Year
2005
Journal title
Tetrahedron
Record number
1088314
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