Title of article :
Synthesis and antagonist activities of 4-aryl-substituted conformationally restricted cyclopentenyl and cyclopentanyl-glutamate analogues
Author/Authors :
Alison T. Ung، نويسنده , , Stephen G. Pyne، نويسنده , , Uta Batenburg-Nguyen، نويسنده , , Andrew S. Davis، نويسنده , , Azlifa Sherif، نويسنده , , François Bischoff، نويسنده , , Anne S.J. Lesage، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2005
Pages :
10
From page :
1803
To page :
1812
Abstract :
The conformationally restricted glutamate analogues, 4-aryl-1-amino-2-cyclopentene-1,3-dicarboxylates and their cyclopentane analogues have been prepared in a diastereoselective manner. Biological studies of and indicates that both compounds are modest antagonists at mGluR2.
Keywords :
Heck reaction , antagonists , metabotropic glutamate receptors
Journal title :
Tetrahedron
Serial Year :
2005
Journal title :
Tetrahedron
Record number :
1088409
Link To Document :
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