Author/Authors :
Alison T. Ung، نويسنده , , Stephen G. Pyne، نويسنده , , Uta Batenburg-Nguyen، نويسنده , , Andrew S. Davis، نويسنده , , Azlifa Sherif، نويسنده , , François Bischoff، نويسنده , , Anne S.J. Lesage، نويسنده ,
Abstract :
The conformationally restricted glutamate analogues, 4-aryl-1-amino-2-cyclopentene-1,3-dicarboxylates and their cyclopentane analogues have been prepared in a diastereoselective manner. Biological studies of and indicates that both compounds are modest antagonists at mGluR2.