Title of article
Synthesis and antagonist activities of 4-aryl-substituted conformationally restricted cyclopentenyl and cyclopentanyl-glutamate analogues
Author/Authors
Alison T. Ung، نويسنده , , Stephen G. Pyne، نويسنده , , Uta Batenburg-Nguyen، نويسنده , , Andrew S. Davis، نويسنده , , Azlifa Sherif، نويسنده , , François Bischoff، نويسنده , , Anne S.J. Lesage، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
10
From page
1803
To page
1812
Abstract
The conformationally restricted glutamate analogues, 4-aryl-1-amino-2-cyclopentene-1,3-dicarboxylates and their cyclopentane analogues have been prepared in a diastereoselective manner. Biological studies of and indicates that both compounds are modest antagonists at mGluR2.
Keywords
Heck reaction , antagonists , metabotropic glutamate receptors
Journal title
Tetrahedron
Serial Year
2005
Journal title
Tetrahedron
Record number
1088409
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