Title of article
Convenient syntheses of 1,1,1,3,3,3-hexafluoro-2-organyl-propan-2-ols and the corresponding trimethylsilyl ethers
Author/Authors
L.A. Babadzhanova، نويسنده , , N.V. Kirij، نويسنده , , Yu.L. Yagupolskii، نويسنده , , W. Tyrra، نويسنده , , D. Naumann، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
7
From page
1813
To page
1819
Abstract
A new convenient synthetic procedure to obtain various 1,1,1,3,3,3-hexafluoro-2-organyl-propan-2-ols and the corresponding trimethylsilyl ethers has been worked out starting from anhydrides or activated esters of carboxylic acids and trimethyl(trifluoromethyl)silane in the presence of tetramethylammonium fluoride. Conditions for the selective formation of 1,1,1,3,3,3-hexafluoro-2-organyl-propan-2-ols as well as the trimethylsilyl derivatives have been found.
Keywords
trifluoromethylation , Synthesis , Alcohols , trimethylsilyl ethers , 2-Hydroxy-1 , 3 , 1 , 1 , 3-hexafluoropropyl , 3
Journal title
Tetrahedron
Serial Year
2005
Journal title
Tetrahedron
Record number
1088410
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