Title of article
The application of vinylogous iminium salt derivatives to an efficient relay synthesis of the pyrrole containing alkaloids polycitone A and B
Author/Authors
John T. Gupton، نويسنده , , Robert B. Miller، نويسنده , , Keith E. Krumpe، نويسنده , , Stuart C. Clough، نويسنده , , Edith J. Banner، نويسنده , , René P.F Kanters، نويسنده , , Karen X. Du، نويسنده , , Kartik M. Keertikar، نويسنده , , Nicholas E. Lauerman، نويسنده , , John M. Solano، نويسنده , , Bret R. Adams، نويسنده , , Daniel W. Callahan، نويسنده , , Barrett A. Little، نويسنده , , Austin B. Scharf، نويسنده , , James ، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
10
From page
1845
To page
1854
Abstract
A new and efficient relay synthesis of the marine natural products polycitone A and B is described. The new strategy relies on the formation of 2,4-disubstituted pyrroles from a vinamidinium salt followed by electrophilic substitution at the 5-position of the pyrrole and Suzuki coupling at the 4-position to produce the tetrasubstituted heterocycle efficiently and with complete control of regiochemistry.
Keywords
marine natural product , Pyrrole , Vinamidinium salt
Journal title
Tetrahedron
Serial Year
2005
Journal title
Tetrahedron
Record number
1088415
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