Title of article
Candida Rugosa lipase-catalyzed kinetic resolution of β-hydroxy-β-arylpropionates and δ-hydroxy-δ-aryl-β-oxo-pentanoates
Author/Authors
Chengfu Xu، نويسنده , , Chengye Yuan، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
18
From page
2169
To page
2186
Abstract
A simple and convenient method was reported for the preparation of optically active β-hydroxy-β-arylpropionates, δ-hydroxy-δ-aryl-β-oxo-pentanoates and their butyryl derivatives via CRL-catalyzed hydrolysis. The optically active products are potential precursors of some chiral pharmaceuticals and natural products.
Keywords
Enantioselectivity , ?-Hydroxy-?-aryl-?-oxo-pentanoates , Hydrolysis , Candia Rugosa lipase (CRL) , ?-Hydroxy-?-arylpropionates
Journal title
Tetrahedron
Serial Year
2005
Journal title
Tetrahedron
Record number
1088446
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