Title of article
Development of resin-to-resin transfer reactions (RRTR) using Sonogashira chemistry
Author/Authors
Judit Tulla-Puche، نويسنده , , George Barany، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
7
From page
2195
To page
2201
Abstract
Sonogashira chemistry can be used according to the ‘resin-to-resin transfer reaction’ (RRTR) concept. Two fragments, one containing the halide moiety and the second one incorporating the alkyne functionality, are anchored on different solid supports using allyl and/or Wang-type linkages. Treatment with Pd(0) cleaves the allyl-linked fragment(s) which subsequently undergo Sonogashira coupling under the same conditions.
Keywords
solid-phase organic synthesis , Sonogashira coupling , Resin-to-resin transfer reactions
Journal title
Tetrahedron
Serial Year
2005
Journal title
Tetrahedron
Record number
1088448
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