Title of article
Biomimetic synthesis of (±)-aculeatin D
Author/Authors
Jack E. Baldwin، نويسنده , , Robert M. Adlington، نويسنده , , Victoria W.-W. Sham، نويسنده , , Rodolfo Marquez، نويسنده , , Paul G. Bulger، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
11
From page
2353
To page
2363
Abstract
A practical, efficient and diastereoselective synthesis of the cytotoxic and antiprotozoal compound aculeatin D () is described, employing a biomimetic oxidative cyclisation cascade reaction to generate the tricyclic system of the natural product. The synthesis proceeds in ten steps from commercially available 1-tetradecanol.
Keywords
Biomimetic synthesis , Aculeatin D , oxidative cyclisation , hypervalent iodine reagents
Journal title
Tetrahedron
Serial Year
2005
Journal title
Tetrahedron
Record number
1088462
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