Title of article
Orthogonality and compatibility between Tsc and Fmoc amino-protecting groups
Author/Authors
Jin Seok Choi، نويسنده , , Hunhui Kang، نويسنده , , Nakcheol Jeong، نويسنده , , Hogyu Han، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
11
From page
2493
To page
2503
Abstract
New deprotection conditions that provide a complete orthogonality between Tsc and Fmoc amino-protecting groups are described. The potential of these orthogonal deprotection conditions was then demonstrated by the efficient solid-phase synthesis of branched peptides and using doubly protected amino acids such as Tsc-Lys(Fmoc)-OH and Fmoc-Lys(Tsc)-OH .
Keywords
Amino-protecting group , Orthogonal deprotection , Branched peptide , TSC , FMOC
Journal title
Tetrahedron
Serial Year
2005
Journal title
Tetrahedron
Record number
1088477
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