Title of article
Novel synthesis of 4-halo-3-hydroxy-2-pyrone: one pot rearrangement–cyclization reaction by magnesium halide
Author/Authors
Takuzo Komiyama، نويسنده , , Yutaka Takaguchi، نويسنده , , Aider T. Gubaidullin، نويسنده , , Vakhid A. Mamedov، نويسنده , , Igor A. Litvinov، نويسنده , , Sadao Tsuboi، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
7
From page
2541
To page
2547
Abstract
Treatment of acetonide protected 4,5-dihydroxy-2-chloroglycidic ester or its rearrangement product, the acetonide protected 4,5-dihydroxy-3-chloro-2-oxo ester, with magnesium halides gave 4-halo-3-hydroxy-2-pyrone in excellent to reasonable yields in one pot. The mechanism of this novel one pot rearrangement–cyclization reaction is also proposed.
Keywords
3-Hydroxy-2-pyrone , Magnesium halide , Darzens condensation , Dichloroacetate , Cyclization
Journal title
Tetrahedron
Serial Year
2005
Journal title
Tetrahedron
Record number
1088482
Link To Document