• Title of article

    Synthesis of functionalized α-amino-phosphine oxides and -phosphonates by addition of amines and aminoesters to 4-phosphinyl- and 4-phosphonyl-1,2-diaza-1,3-butadienes

  • Author/Authors

    Francisco Palacios، نويسنده , , Domitila Aparicio، نويسنده , , Yago L?pez، نويسنده , , Jes?s M. de los Santos، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2005
  • Pages
    16
  • From page
    2815
  • To page
    2830
  • Abstract
    1,2-Diaza-1,3-butadienes derived from phosphine oxides and phosphonates and with optically active substituents on N-1 and C-3 are obtained by 1,4-elimination from chlorohydrazonoalkyl-phosphine oxides and -phosphonates in the presence of bases. Michael addition (1,4-addition) of ammonia, aliphatic and aromatic amines and aminoesters to these azo-alkenes gives functionalized α-amino-phosphine oxides and -phosphonates.
  • Keywords
    Michael addition , hydrazones , ?-Amino-phosphonates , 3-butadienes , 3-butadienes , 2-diaza-1 , 2-diaza-1 , 4-Phosphinyl-1 , ?-Amino-phosphine oxides , 4-Phosphonyl-1
  • Journal title
    Tetrahedron
  • Serial Year
    2005
  • Journal title
    Tetrahedron
  • Record number

    1088510