Title of article
Synthesis of a caryophyllene isoprenologue, a potential diterpene natural product
Author/Authors
Simon F.R. Hinkley، نويسنده , , Nigel B. Perry، نويسنده , , Rex T. Weavers، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
10
From page
3671
To page
3680
Abstract
(−)-β-Caryophyllene has been converted into three stereoisomers of a new bicyclic compound that is structurally related to the known macrocyclic diterpene, flexibilene, in the same way β-caryophyllene is related to humulene. Key steps are selective cleavage of caryophyllene, addition of a five carbon component by a Wittig reaction and McMurry cyclization.
Keywords
Bicyclic diterpene , Wittig reaction , Warren modification , McMurry cyclization , Flexibilene
Journal title
Tetrahedron
Serial Year
2005
Journal title
Tetrahedron
Record number
1088587
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