Title of article
Stereocontrol in cycloadditions of (1Z,4R*,5R*)-1-arylmethylidene-4-benzoylamino-5-phenylpyrazolidin-3-on-1-azomethine imines
Author/Authors
Lidija Pezdirc، نويسنده , , Vasko Jovanovski، نويسنده , , David Bevk، نويسنده , , Renata Jak?e، نويسنده , , Samo Pirc، نويسنده , , Anton Meden، نويسنده , , Branko Stanovnik، نويسنده , , Jurij Svete، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
14
From page
3977
To page
3990
Abstract
Cycloadditions of (1Z,4R*,5R*)-4-benzoylamino-5-phenylpyrazolidin-3-on-1-azomethine imines to olefinic dipolarophiles were studied. Stereochemistry of cycloadditions to azomethine imines was found to be controlled by stereodirecting phenyl group at position 3, as well as by the ortho-substituents at the aromatic ring at position 1′. The structures of dipoles and products were confirmed by NMR and X-ray diffraction.
Keywords
2-a]pyrazoles , 3-dipolar cycloadditions , azomethine imines , Stereochemistry , peptidomimetics , 1
Journal title
Tetrahedron
Serial Year
2005
Journal title
Tetrahedron
Record number
1088617
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