Title of article
Synthesis of alkyl 4-(diethoxymethyl)-3-pyridin-3-ylisoxazole-5-carboxylates: useful scaffold for highly functionalised 3-(pyridin-3-yl)isoxazoles
Author/Authors
José Luis Garc?a Ruano، نويسنده , , Cristina Fajardo، نويسنده , , M. Rosario Mart?n، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
9
From page
4363
To page
4371
Abstract
The methyl 4-(diethoxymethyl)-3-(pyridin-3-yl)isoxazole-5-carboxylate obtained by domino 1,3-dipolar cycloaddition and elimination starting of pyridine-3-nitrile oxide and methyl 4,4-diethoxy-3-p-tolylsulfinylbut-2-enoate is a convenient scaffold for the synthesis of other new highly functionalised 3-pyridin-3-ylisoxazoles-5-carboxylic acid derivatives and isoxazole-annulated heterocycles.
Keywords
Cycloaddition , sulfoxides , Sulfones , Nitrile oxides , 3-Pyridin-3-ylisoxazoles
Journal title
Tetrahedron
Serial Year
2005
Journal title
Tetrahedron
Record number
1088654
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