Title of article
Pyridazine derivatives. Part 40: Reactivity of 5-alkynylpyridazin-3(2H)-ones toward hydrochloric acid
Author/Authors
Alberto Coelho، نويسنده , , Hector Novoa de Armas، نويسنده , , Oswald M. Peeters، نويسنده , , Norbert Blaton، نويسنده , , Mario Alvarado، نويسنده , , Eddy Sotelo، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2005
Pages
7
From page
4785
To page
4791
Abstract
5-Alkynylpyridazin-3(2H)-ones or 5-(2-chloroalkenyl)pyridazin-3(2H)-ones were isolated during the cleavage of the methoxymethyl group in a series of 5-alkynyl-2-methoxymethylpyridazin-3(2H)-ones by treatment with hydrochloric acid. The efficient and selective cleavage of the methoxymethyl group in these compounds can be performed under mild conditions by employing aluminium chloride.
Keywords
pyridazinones , Electrophilic addition , X-ray diffraction , Protecting groups
Journal title
Tetrahedron
Serial Year
2005
Journal title
Tetrahedron
Record number
1088699
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