Title of article :
Bisphosphonate prodrugs: synthesis of new aromatic and aliphatic 1-hydroxy-1,1-bisphosphonate partial esters
Author/Authors :
Maelle Monteil، نويسنده , , Erwann Guenin، نويسنده , , Evelyne Migianu، نويسنده , , Didier Lutomski، نويسنده , , Marc Lecouvey، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2005
Abstract :
Methods for the preparation of various 1-hydroxy-1,1-bisphosphonate partial esters were developed. They were obtained from (alkyl or phenyl) bis(trimethylsilyl) phosphite and aromatic or aliphatic acid chlorides, followed by methanolysis.
Keywords :
bisphosphonate , Arbusov reaction
Journal title :
Tetrahedron
Journal title :
Tetrahedron
