Title of article :
Reactions of (Z)-3-aryl-3-chloropropenals with nucleophiles: stereoselective formation of (E)-vinylogous esters, (E)-vinylogous amides, and vinamidinium salts
Author/Authors :
Stuart Clough، نويسنده , , John Gupton، نويسنده , , S. Adepeju Ligali، نويسنده , , Matthew Roberts and Philip Rowe، نويسنده , , David Driscoll، نويسنده , , Scott Annett، نويسنده , , Alisa Hewitt، نويسنده , , Matthew Hudson، نويسنده , , Edward Jackson، نويسنده , , Robert Miller، نويسنده , , Bradley Norwood، نويسنده , , Rene Kanters، نويسنده , , Hadley Wyre، نويسنده , , Heather Petruzzi، نويسنده ,
Abstract :
The highly stereoselective conversions of (Z)-3-aryl-3-chloropropenals to (E)-3-alkoxy-3-arylpropenals, to (E)-3-aryl-3-morphorlinopropenals, and to vinamidinium salts are reported. The stereochemical assignments were based on 2D-NMR experiments.
Keywords :
Vinylogous esters , Vinylogous amides , vinamidinium salts , 3-Chloropropenals
