• Title of article

    Shimalactone A, a novel polyketide, from marine-derived fungus Emericella variecolor GF10

  • Author/Authors

    Hong Wei ، نويسنده , , Takuya Itoh، نويسنده , , Masahiro Kinoshita، نويسنده , , Naoyuki Kotoku، نويسنده , , Shunji Aoki، نويسنده , , Motomasa Kobayashi، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2005
  • Pages
    5
  • From page
    8054
  • To page
    8058
  • Abstract
    Shimalactone A (), a novel polyketide having bicyclo[4.2.0]octadiene and oxabicyclo[2.2.1]heptane units, was isolated from a cultured marine fungus of Emericella variecolor GF10. The stereo structure of was deduced from 2D NMR and X-ray crystallographic analyses of and its derivatives. The absolute structure of was determined by application of the CD allylic benzoate rule to the benzoate derivative of . Shimalactone A () induced neuritogenesis at 10 μg/mL against neuroblastoma Neuro 2A cells.
  • Keywords
    X-ray analysis , Shimalactone A , Polyketide , Emericella variecolor , Marine derived fungus
  • Journal title
    Tetrahedron
  • Serial Year
    2005
  • Journal title
    Tetrahedron
  • Record number

    1089025